Microinjection of kainic acid into the CA3 subfield of hippocampus in anest
hetized rats elicited seizure-like hippocampal EEG activity that persisted
for more than 180 minutes. There was a concomitant rise in plasma prolactin
level that peaked at 15 to 20 minutes but endured less than 60 minutes. We
conclude that plasma prolactin exhibited only transient elevations during
experimental temporal lobe status epilepticus in rats.