Progressive changes in the fluorescein and indocyanine green angiogram in acute idiopathic maculopathy

Aims/background: To report progressive changes in the fluorescein and indoc yanine green angiograms of a patient with acute idiopathic maculopathy (AIM ). Methods: Over a two-year period, the patient underwent repeated ophthalm oscopic examinations and fluorescein (FA) and indocyanine green (ICG) angio graphy. Results: The patient presented with subretinal neovascularization i n his right eye. He developed recurrences after laser photocoagulation and surgical removal of the neovascular complex. One year later, he experienced a sudden loss of vision in his left eye with a maculopathy consistent with AIM. The maculopathy resolved after two weeks with poor vision. During the acute stage, FA showed lobular hyperfluorescence in the early phase and po oling in the late phase of the angiogram. In the resolved stage of the dise ase, FA showed irregular window defects and blockage. ICG revealed late hyp erfluorescence of the macula in the acute stage. In the resolved stage of t he disease, early hypofluorescence was noted in the ICG, which persisted th roughout the late phase. Conclusion: This patient had poor vision in his ri ght eye as a result of subretinal retinal neovascularization and poor visio n in his left eye from a severe form of AIM. FA and ICG differed markedly d uring the acute and resolved stages of AIM. All cases of idiopathic subreti nal neovascularization should be carefully evaluated to exclude AIM as the primary disease.