Amiodarone induced retrobulbar neuritis. Report of one case

We report a 66 years old male, with an ophtalmologic history of long sighte dness, admitted to the hospital due to paroxysmal atrial fibrillation crise s in the context of a coronary heart disease. He was treated with iv amioda rone receiving a total dose of 6 g in 72 hours. After the third day of trea tment, the patient noticed a correction of his long sightedness and 24 h In ter, he complained of blurred vision and orbital frontal headache. Visual f ield examination revealed a concentric retraction of visual field and a cen trocecal scotoma in both eyes. Amiodarone was withdrawn and dexametasone tr eatment was begun. Three days after amiodarone discontinuation, sight impro ved and visual field returned to normal. Although retrobulbar neuritis has been associated to various drugs, amiodarone has not been considered as a p ossible agent.