Meta-analysis by random effect modelling in generalized linear models

Authors
Aitkin, M
Citation
M. Aitkin, Meta-analysis by random effect modelling in generalized linear models, STAT MED, 18(17-18), 1999, pp. 2343-2351
Citations number
26
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
STATISTICS IN MEDICINE
ISSN journal
02776715 → ACNP
Volume
18
Issue
17-18
Year of publication
1999
Pages
2343 - 2351
Database
ISI
SICI code
0277-6715(19990930)18:17-18<2343:MBREMI>2.0.ZU;2-D
Abstract
The meta-analysis of multi-centre trials can be based on either fixed or ra ndom effect models. This argues for the general use of random effect models , and illustrates the value of non-parametric likelihood (NPML) analysis of such trials. The same general approach unifies administrative 'league anal yses in epidemiological and other studies. Several examples of the NPML ana lysis are given, a 70-centre trial. Copyright (C) 1999 John Wiley & Sons, L td.