Synthesis and biological activity of azanucleosides

Citation
M. Yokoyama et A. Momotake, Synthesis and biological activity of azanucleosides, SYNTHESIS-S, (9), 1999, pp. 1541-1554
Citations number
42
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
9
Year of publication
1999
Pages
1541 - 1554
Database
ISI
SICI code
0039-7881(199909):9<1541:SABAOA>2.0.ZU;2-4
Abstract
In recent years nucleosides and nucleotides known to be DNA and RNA subunit s have become an increasingly important subject of research in the field of pharmaceutical science. In particular, recent studies deal with the synthe sis and biological activity of novel types of nucleosides and nucleotides. In this short review, we will summarize the chemistry of the so-called azan ucleosides which have an azaribofuranosyl moiety, together with our recent work in this area.