A new simple route for the synthesis of (+/-)-2-azetidinones starting frombeta-enaminoketoesters

Authors
De Risi, C Pollini, GP Veronese, AC Bertolasi, V
Citation
C. De Risi et al., A new simple route for the synthesis of (+/-)-2-azetidinones starting frombeta-enaminoketoesters, TETRAHEDR L, 40(38), 1999, pp. 6995-6998
Citations number
5
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
38
Year of publication
1999
Pages
6995 - 6998
Database
ISI
SICI code
0040-4039(19990917)40:38<6995:ANSRFT>2.0.ZU;2-9
Abstract
beta-Enaminoketoesters, obtained by metal-catalyzed reaction between alkyl acetoacetates and alkyl cyanoformates, are useful starting materials for ra pid access to beta-acetyl-dehydroaspartic acrid derivatives which could be transformed into (+/-)-2-azetidinones bearing a 1-hydroxy-ethyl substituent through suitable reductive processes. (C) 1999 Elsevier Science Ltd. All r ights reserved.