Y. Rao et al., Chemiluminescence flow-injection determination of furosemide based on a rhodamine 6G sensitized cerium(IV) method, ANALYT CHIM, 396(2-3), 1999, pp. 273-277
A flow-injection method is described for the determination of furosemide in
the range 1.0-50.0 mu mol l(-1), with a detection Limit of 0.22 mu mol l(-
1) and a relative standard deviation of 2.1% at 10 mu mol l(-1) (n = 10). T
he method is based on the chemiluminescence reaction of furosemide with cer
ium (IV) in sulphuric acid, sensitized by rhodamine 6G. By applying the met
hod to tablets and injection solutions, it was found that the present metho
d is relatively free from interference and tolerable to turbid solutions. (
C)1999 Elsevier Science B.V. All rights reserved.