Regioselective modification of the sugar moiety in pyrimidine nucleosides via a 4 ',5 '-dehydro-2 ',3 '-anhydrouridine intermediate

Authors
Hirota, K Takasu, H Tsuji, Y Sajiki, H
Citation
K. Hirota et al., Regioselective modification of the sugar moiety in pyrimidine nucleosides via a 4 ',5 '-dehydro-2 ',3 '-anhydrouridine intermediate, CHEM COMMUN, (18), 1999, pp. 1827-1828
Citations number
33
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
18
Year of publication
1999
Pages
1827 - 1828
Database
ISI
SICI code
1359-7345(19990921):18<1827:RMOTSM>2.0.ZU;2-I
Abstract
3'-Substituted pyrimidine nucleoside derivatives are obtained in moderate t o high yields by the reaction of 1-(2',3'-anhydro-5'-deoxy-4',5'-didehydro- alpha-L-erythro-pentofuranosyl)uracil with nucleophiles without the formati on of the corresponding 2'-adduct.