Enantiomer separation of glycerin sulfides and glycerin selenides with a chiral stationary phase of cellulose derivative

Cellulose-tris(3, 5-dimethylphenylcarbamate) was prepared and immobilized o nto a mesopore spherical aminopropylated silica gel. The final product was used as a chiral stationary phase for the enantioseparation of a series of glycerin sulfides and glycerin selenides. Some enantiomers of the monosulfi des and monoselenides could be separated satisfactorily, but the bisulfides could not at all. The structural characteristic of the samples that influe nce chiral discrimination was disscused. The effect of 2-propanol concentra tion in the mobile phase on the retention and resolution was also investiga ted.