Synaptic neurone activity under applied 50 Hz alternating magnetic fields

The effect of 50 Hz alternating magnetic fields of 10-150 Gauss (1-15 mT) i ntensity on neurone synaptic activity for glutamate and acetylcholine has b een studied. The applied 50 Hz alternating magnetic field does not modify t he synaptic activity induced by glutamate or acetylcholine on neurones. It has been observed that both caffeine and glutamate induce similar effects, either stimulation or inhibition, on different neurone types. It is shown t hat applied 50 Hz alternating magnetic fields mimic the synaptic effect of glutamate. A mimic effect has also been observed between the induced effect by applying 50 Hz alternating magnetic held on neurones and the one induce d by caffeine and glutamate on the same neurone. The application of Ringer solutions with different concentrations of Ca2+/K+ ions suggest that Ca2+ i ons are involved in the elicited responses to either caffeine, glutamate or 50 Hz magnetic fields. Our conclusion is that the observed mimic induced e ffects for 50 Hz alternating magnetic ;fields, caffeine and glutamate on ne urones corroborate that Ca2+ ions are the cytosolic effecters of the applie d 50 Hz alternating magnetic fields interaction with neurone plasma membran e. (C) 1999 Elsevier Science Inc. All rights reserved.