Raynaud's phenomenon in older adults - Diagnostic considerations and management

Citation
Sm. Ling et Fm. Wigley, Raynaud's phenomenon in older adults - Diagnostic considerations and management, DRUG AGING, 15(3), 1999, pp. 183-195
Citations number
67
Categorie Soggetti
Pharmacology,"Pharmacology & Toxicology
Journal title
DRUGS & AGING
ISSN journal
1170229X → ACNP
Volume
15
Issue
3
Year of publication
1999
Pages
183 - 195
Database
ISI
SICI code
1170-229X(199909)15:3<183:RPIOA->2.0.ZU;2-R
Abstract
Raynaud's phenomenon (RP) is characterised by sensitivity to cold temperatu res associated with either biphasic or uniphasic change in colour of the di gits. Since few studies are available which include older adults, the preva lence of RP in the older adult population is estimated from surveys or stud ies of the general population. The causes of RP in older adults may differ significantly from those in young adults and, therefore, so would the evalu ation of RP. Because of comorbities that accompany advancing age, the manag ment of RP in older adult patients must take into consideration toxicity an d adverse reactions that may develop, especially in the frail individual. A lthough nonpharmacological therapy is preferable, slow-release calcium anta gonists provide a relatively well tolerated and effective treatment for mod erate to severe RP in older adult patients. Aggressive treatment including: hospitalisation is appropriate for older adult patients during periods of critical digital ischaemia associated with RP.