Impaired anticipatory finger grip-force adjustments in a case of cerebellar degeneration

We describe adjustments in grip force as a consequence of fluctuations in i nertial load force during vertical movements of the upper limb in a patient with cerebellar degeneration. Normally grip force is adapted to load-force fluctuations, in particular to the maximum load force, which occurs early in upward movements and late in downward movements. Increased grip force du ring movement was observed in the patient, but the timing of maximum grip f orce was not different between upward and downward movements. This suggests impaired cerebellar prediction of the dynamic consequences of voluntary mo vement.