Synthesis of N-[4-(alkyl)cyclohexyl]-substituted benzamides with anti-inflammatory and analgesic activities

Authors
Pau, A Boatto, G Palomba, M Asproni, B Cerri, R Palagiano, F Filippelli, W Falcone, G Motola, G
Citation
A. Pau et al., Synthesis of N-[4-(alkyl)cyclohexyl]-substituted benzamides with anti-inflammatory and analgesic activities, FARMACO, 54(8), 1999, pp. 524-532
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
54
Issue
8
Year of publication
1999
Pages
524 - 532
Database
ISI
SICI code
0014-827X(19990830)54:8<524:SONBWA>2.0.ZU;2-S
Abstract
Two series of N-[4-(alkyl)cyclohexyl]-substituted benzamides, i.e. a series of N-[4-(relf-butyl)cyclohexyl]-substituted benzamides and a series of N-[ 4-(ethyl)cyclohexyl]-substituted benzamides, were synthesised and evaluated for their anti-inflammatory and analgesic potencies, and gastrointestinal irritation liability. (C) 1999 Elsevier Science S.A, All rights reserved.