HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: Strain distribution patterns of 632 alleles

Authors
Pravenec, M Kren, V Krenova, D Bila, V Zidek, V Simakova, M Musilova, A van Lith, HA van Zutphen, LFM
Citation
M. Pravenec et al., HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: Strain distribution patterns of 632 alleles, FOL BIOL, 45(5), 1999, pp. 203-215
Citations number
38
Categorie Soggetti
Experimental Biology
Journal title
FOLIA BIOLOGICA
ISSN journal
00155500 → ACNP
Volume
45
Issue
5
Year of publication
1999
Pages
203 - 215
Database
ISI
SICI code
0015-5500(1999)45:5<203:HABRIS>2.0.ZU;2-U
Abstract
The HXB/Ipcv and BXH/Cub sets of recombinant inbred (RI) strains were deriv ed from the spontaneously hypertensive rats (SHR/OlaIpcv) and normotensive Brown Norway (BN-Lx/Cub) rats. The RI strains were produced as a model syst em for genetic and correlation analysis of spontaneous hypertension and oth er risk factors of cardiovascular disease such as insulin resistance and dy slipidemia. The RI strains were phenotyped in multiple hemodynamic and meta bolic traits. In the current study, we describe strain distribution pattern s of 632 genetic markers.