Objective Long-term follow-up of women who have undergone transcervical res
ection of the endometrium (TCRE), and evaluation of the uterine endometrium
and cavity in these women.
Design Transvaginal ultrasound examination (TVS) with hydrosonography and h
ysteroscopy, including biopsies, was carried out in 61 women, 19-67 months
(mean 40 months) after transcervical endometrial resection.
Results The age range of the women was 37-58 years (mean 48 years). Of 61 w
omen, 67% had amenorrhoea or hypomenorrhoea, 28% had withdrawal bleeding of
normal amounts and three women suffered from polymenorrhoea. Of 40 women w
ith dysmenorrhoea before treatment, 18 still had cyclic pain afterwards. In
three women, dysmenorrhoea developed postoperatively. At ultrasound examin
ation, an echo from the uterine cavity was found in 95% of the women and an
echo of 5 mm or more was seen in 22%. Crypts and occlusions were present i
n 19% and synechiae in 4% of the women. For technical reasons, hydrosonogra
phy could not easily be done. At hysteroscopy signs of endometrium were fou
nd in 85% of the women, and synechiae were present in all women. The uterin
e cavity was partly occluded and narrowed. One woman bad a total occlusion
of the uterine cavity. Histopathological examination of the biopsies or cur
ettage specimens from the uterine cavity showed endometrial tissue in 67% o
f the women.
Conclusions Residual endometrium was found in most women after TCRE and, th
erefore, if hormone replacement therapy is to be used, a combination of oes
trogen with gestogen should be recommended. Intracavitary synechiae were pr
esent in most women after TCRE. The synechiae may have contributed to the c
yclic pain experienced by 20 women after treatment. However, the synechiae
did not seem to conceal the withdrawal bleeding or menstruation. If women w
ho have undergone TCRE develop symptoms such as bleeding and/or pain, both
vaginal ultrasound and hysteroscopy with directed biopsies should be recomm
ended.