We analyzed data from two national surveys to estimate the shortterm work d
isability associated with thirty-day major depression. Depressed workers we
re found to have between 1.5 and 3.2 more short-term work-disability days i
n a thirty-day period than other workers had, with a salary-equivalent prod
uctivity loss averaging between $182 and $395. These workplace costs are ne
arly as large as the direct costs of successful depression treatment, which
suggests that encouraging depressed workers to obtain treatment might be c
ost-effective for some employers.