Studies on biologically active phosphorus compounds. Part 30 - Synthesis and insecticidal activity of O-aryl O-(1,2,2,2-tetrachloroethyl)phosphoramidothioates and their thiophosphoric hydrazides

O-ArylO-(1, 2, 2, 2-tetrachoroethyl)phosphoramidothioates 3a-h and their th iophosphoric hydrazides 4a-e weve synthesized by reactions of O-aryl O-(1,2 ,2,2-tetrachoroethyl) thiophosphorochloridates 2 with amines and hydrazines , respectively. Their structures were characterized by elemental analysis I R H-1 NMR, P-31 NMR, and MS. The O-aryl O-(1,2,2,2-tetrachloroethyl) thioph osphoric hydrazides 4a-d (R-2=H) can be transformed into 1,3,4,2-oxadiazaph ospholanes 5a-d by the reaction of triethylamine. The results of preliminar y bioassays indicated that some of the title compounds have good insecticid al activities against nematodes (Meloidogyne spp.) and pea aphids. (C) 1999 John Wiley & Sons, Inc.