Spontaneous ovarian hyperstimulation syndrome and deep vein thrombosis in pregnancy

This report describes a case of spontaneous ovarian hyperstimulation syndro me (OHSS) occurring in a pregnant woman carrying the factor V Leiden mutati on, Even though prophylactic treatment for thrombo-embolism was adopted by administering low molecular weight heparin, the pregnancy was complicated b y thromboses of the left subclavian, axillary, humeral and internal jugular veins during the second trimester of gestation, The pregnancy was managed conservatively and a healthy newborn was delivered at term. In order to avo id unnecessary laparotomy, we emphasize the importance of careful diagnosis in order to differentiate spontaneous OHSS from ovarian carcinoma, as well as the necessity to look for the presence of coagulation disorders in wome n affected by OHSS.