Mp. Milad et E. Olson, Factors that increase the risk of leakage during surgical removal of benign cystic teratomas, HUM REPR, 14(9), 1999, pp. 2264-2267
The contents of mature cystic teratomas can be a potent irritant resulting
in chemical peritonitis, Using a retrospective cohort, we examined the vari
ous risk factors for leakage of benign cystic teratomas during laparoscopy
and laparotomy, Cyst leakage of the benign cystic teratoma contents was the
primary endpoint. In all, 158 women underwent surgery for a total of 178 o
varian benign cystic teratomas, Statistical analysis was performed using ch
i(2), Mann-Whitney U and multivariate logistic regression analysis, A total
of 115 benign cystic teratomas was successfully removed without intra-oper
ative leakage and 63 underwent intraoperative leakage either at laparoscopy
or laparotomy, The likelihood of success of removing the benign cystic ter
atoma intact was unrelated to age, pre-operative size or surgical technique
, There was no difference among cystectomies performed by laparotomy in sur
geon experience or the presence of adhesions. However, surgeons with more l
aparoscopic experience (>35 laparoscopies/year) were less likely to have in
tra-operative leakage (relative risk: 0.5, 95% confidence interval: 0.2, 1.
2) compared to surgeons with less experience (<20/year) at cystectomy (26.1
versus 51.2% respectively), Oophorectomy significantly reduced the frequen
cy of intra-operative leakage at both laparoscopy and laparotomy (14.7%), T
hese findings suggest that laparoscopic experience can reduce the risk of l
eakage at cystectomy, At laparotomy, lack of surgeon postgraduate years of
experience was not a risk factor for leakage.