An experimental model of 70% hepatectomy in the rat using a microsurgical t
echnique is described. An operative microscope (Carl Zeiss 10 Y 2) dissecti
on made it possible to identify the hilar anatomical variations and then to
avoid unexpected damage to the arterio-portal and biliary branches belongi
ng to the remaining hepatic parenchyma. The use of this microsurgical techn
ique allows for a more homogenous experimental model because it avoids the
functional impairment of the remaining liver.