Intra-abdominal and retroperitoneal liposarcomas

Nine primary intra-abdominal or retroperitoneal liposarcomas, of which eigh t were recurrent tumors, were surgically resected and enrolled in this stud y Histopathological examination of primary tumors revealed that the number of well-differentiated, pleomorphic and myxoid type was two, four and three , respectively. In two recurrent cases, histological differentiation change d from well-differentiated type into myxoid or pleomorphic types. Prognoses of patients with large tumors (greater than or equal to 20 cm) were signif icantly poorer than for patients with small tumors (< 20 cm). Labelling ind ex of Ki-67 of recurrent tumors increased in two cases. The tumor size affe cted prognoses,of patients with intraabdominal or retroperitoneal liposarco ma. Combined resection was important to get a tumor-free margin.