Quantification of human cytomegalovirus DNA in amniotic fluid of mothers of congenitally infected fetuses

Citation
Mg. Revello et al., Quantification of human cytomegalovirus DNA in amniotic fluid of mothers of congenitally infected fetuses, J CLIN MICR, 37(10), 1999, pp. 3350-3352
Citations number
15
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
37
Issue
10
Year of publication
1999
Pages
3350 - 3352
Database
ISI
SICI code
0095-1137(199910)37:10<3350:QOHCDI>2.0.ZU;2-P
Abstract
A quantitative PCR assay was used to quantitate human cytomegalovirus DNA i n amniotic fluid of mothers of 21 fetuses with congenital infection. Seven fetuses presented ultrasound abnormalities or were born with symptoms, wher eas 14 fetuses were subclinically infected. Although the median DNA level w as higher in symptomatic fetuses, the difference was not statistically sign ificant (pr 0.09).