It is often stated in the literature concerning D = 4, 6 compact type IIB o
rientifolds that tadpole cancellation conditions (i) uniquely fix the gauge
group (up to Wilson lines and/or moving of branes) and (ii) are equivalent
to gauge anomaly cancellation. We study the relationship between tadpole a
nd anomaly cancellation conditions and qualify both statements. In general
the tadpole cancellation conditions imply gauge anomaly cancellation but ar
e stronger than the latter conditions in D = 4, N = 1 orientifolds. We also
find that tadpole cancellation conditions in Z(N) D = 4;6 compact orientif
olds do not completely fix the gauge group and we provide new solutions dif
ferent from those previously reported in the literature.