Muscular pain in some rheumatic diseases

Muscular pain can accompany many clinical disorders, such as infective ailm ents [Lyme disease, human immunodeficiency virus infection, and other disea ses], vasculitides [e.g., microscopic polyangiitis and Takayasu's arteritis ], endocrinopathies [e.g., hypothyroid ism], genetic diseases [e.g., famili al Mediterranean fever], and toxicity from drugs. In some rheumatic diseases, chronic myalgia is not the main symptom but may be so relevant that it creates differential diagnosis problems with fibrom yalgia [FMS]. For example, FMS can accompany osteoporosis. Differential diagnosis between primary and secondary FMS is not difficult i f an accurate history and thorough clinical examination are utilized with a ppropriate tests.