We report a rare case of recurrent chyluria in a 64-year-old man, who had u
ndergone sclerosing therapy for chyluria with complete remission 40 years p
reviously. The chyluria recurred 4 months before the present hospital admis
sion. The patient presented with acute urine retention and weight loss of 6
kg during the past 6 months. Urine biochemistry studies showed elevated co
ncentrations of albumin (0.7 g/dL), globulin (0.6 g/dL), cholesterol (0.59
mmol/L), and triglyceride (0.89 mmol/L), confirming the diagnosis of chylur
ia. Intravenous urography showed a substantial filling defect in the urinar
y bladder. Cystoscopy revealed milky urine flowing out of the right uretera
l orifice, and a large chylous coagulum presenting as a cyst-like mass in t
he urinary bladder. The chyluria was successfully treated with sclerosing t
herapy with injection of 76% Urografin (Shering AG, Berlin, Germany) into t
he right upper urinary tract, and the chylous coagulum was evacuated endosc
opically. No evidence of chyluria recurrence has been noted during a year o
f follow-up, and the patient has regained 6 kg of body weight This particul
ar presentation of chylous coagulum in a chyluria patient has not been prev
iously reported in the literature.