Regulation of glomerular cell number by apoptosis

Authors
Citation
J. Savill, Regulation of glomerular cell number by apoptosis, KIDNEY INT, 56(4), 1999, pp. 1216-1222
Citations number
81
Categorie Soggetti
Urology & Nephrology","da verificare
Journal title
KIDNEY INTERNATIONAL
ISSN journal
00852538 → ACNP
Volume
56
Issue
4
Year of publication
1999
Pages
1216 - 1222
Database
ISI
SICI code
0085-2538(199910)56:4<1216:ROGCNB>2.0.ZU;2-G
Abstract
While commonly viewed as leading to glomerular scarring and end-stage renal failure, glomerular cell proliferation may be a beneficial response that p romotes the injured glomerulus to return to its proper function. This brief review looks at the potentially counterbalancing influences that cause glo merular cells to survive, undergo mitosis, differentiate or die.