Cedh. De Laet et al., Incremental cost of medical care after hip fracture and first vertebral fracture: The Rotterdam Study, OSTEOPOR IN, 10(1), 1999, pp. 66-72
The aim of this study was to estimate the additional cost of medical care (
the incremental cost) caused by incident hip and vertebral fractures, using
a matched case cohort design within a longitudinal followup study. Inciden
t hip fractures were recorded using the regular follow-up system of the Rot
terdam Study. Incident vertebral fractures were recorded by morphometric co
mparison of spinal radiographs taken at intervals of 2.2 years on average.
The matched control group was randomly selected from other participants of
the Rotterdam Study in whom no fracture occurred during follow-up, but who
were otherwise comparable at baseline. Cases were matched for age, gender,
self-perceived health, ability to perform activities of daily life, living
situation and general practitioner. Medical expenditure was assessed by ret
rieval of the general practice medical records and by recording all hospita
l and nursing home admissions, and all general practice and outpatient visi
ts. Pharmaceutical consumption was recorded through the computerized record
s of the central pharmacy. Valid results were obtained for 44 pairs (91%) i
n the hip fracture and for 42 pairs (93%) in the vertebral fracture group.
Cost of medical consumption in the year before the hip fracture was similar
in patients and control subjects, but the incremental cost in the first ye
ar after the hip fracture was almost US$10 000. In the second year after hi
p fracture the incremental cost was still about $1000. Accounting for the e
xcess mortality in hip fracture patients had little effect on cost in the f
irst year, but cost in the second year was doubled to almost $2000. For ver
tebral fractures, we did not detect important acute care costs, but these f
ractures were associated with a yearly recurrent incremental cost of over $
1000. However, almost half this difference was already present before the o
ccurrence of the fracture, and was attributable to hospital admissions. The
remainder of the incremental cost was mainly due to pharmaceutical consump
tion and to a lesser extent to admissions to orthopedic surgery wards. We c
onclude that hip fractures cause excess mortality and an important incremen
tal cost especially during the first year, and that these could probably be
avoided by prevention of hip fractures. For vertebral fractures we found n
o evidence of important acute care costs but we observed a yearly returning
incremental cost. Part of this incremental cost, however, was pre-existing
and might therefore by caused by co-morbidity.