The biotransformation of ent-kaur-16-en-19-oic acid by Rhizopus stolonifer

Citation
Ea. Silva et al., The biotransformation of ent-kaur-16-en-19-oic acid by Rhizopus stolonifer, PHYTOCHEM, 52(3), 1999, pp. 397-400
Citations number
18
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
52
Issue
3
Year of publication
1999
Pages
397 - 400
Database
ISI
SICI code
0031-9422(199910)52:3<397:TBOEAB>2.0.ZU;2-N
Abstract
Microbial transformation of ent-kaur-16-en-19-oic acid was carried out with R. stolonifer. After seven days of incubation, two metabolites, ent-7 alph a-hydroxy-kaur-16-en-19-oic acid and ent-12 beta-hydroxy-kaur-9(11),16-dien -19-oic acid, were isolated as a result of hydroxylation and hpdroxylation/ dehydrogenation, respectively. Incubation for 15 days also afforded ent-16 beta,17-dihydroxy-kauran-19-oic acid. The metabolites were identified by sp ectroscopic methods. (C) 1999 Elsevier Science Ltd, All rights reserved.