In recent times there has been a growing research interest in palm oil, one
of the major edible plant oils in the tropical countries, because of the l
ink between dietary fats and coronary heart disease. Obtained from a tropic
al plant, Elaesis guineensis, it has a polyunsaturated fatty acid/saturated
fatty acid ratio close to unity and a high amount of antioxidant vitamin A
precursors and vitamin E. Palm oil is consumed in the fresh state and/or a
t various levels of oxidation. Feeding experiments in various animal specie
s and humans have highlighted the beneficial role of fresh palm oil to heal
th. These benefits include reduction in the risk of arterial thrombosis and
atherosclerosis, inhibition of cholesterol biosynthesis and platelet aggre
gation, and reduction in blood pressure. However, a considerable amount of
the commonly used palm oil is in the oxidized state which possesses potenti
al dangers to the physiological and biochemical functions of the body. Oxid
ation is as a result of processing the oil for various culinary purposes. S
tudies have revealed that relative to fresh palm oil, oxidized palm oil ind
uces an adverse plasma lipid profile, free fatty acids, phospholipids and c
erebrosides. Additionally, oxidized palm oil induces reproductive toxicity
and organotoxicity particularly of the kidneys, lungs, liver and heart. Ava
ilable evidence suggests that at least part of the oxidized oil impact on h
ealth reflects generation of toxicants due to oxidation. The reduction of t
he dietary level of oxidized oil and/or the level of oxidation may reduce t
he health risk associated with consumption of oxidized fats.