Choosing an antibiotic strategy for adult respiratory tract infections

Treatment of sinusitis: For both acute rhinosinusitis in patients with no p ast history where S. pneumoniae and H. influenzae are the main causal agent s, or recurrent sinusitis in a chronic background where anaerobic bacteria are increasingly implicated, pristinamycin is one of the rare-compounds whi ch can be expected to be effective and isa treatment of choice for an empir ical strategy. Lower respiratory tract infections: Besides high-risk subjects with non-mic robiologically proven bronchial infection, where enterobacteriaceae could i nvolve a pristinamycin is a useful alternative to the conventional strategy (ie: amoxicillin, macrolides and cotrimoxazole) in the treatment of LRT in fection.