A divergent approach to cryptotackieine and cryptosanguinolentine alkaloids

Authors
Fresneda, PM Molina, P Delgado, S
Citation
Pm. Fresneda et al., A divergent approach to cryptotackieine and cryptosanguinolentine alkaloids, TETRAHEDR L, 40(40), 1999, pp. 7275-7278
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
40
Year of publication
1999
Pages
7275 - 7278
Database
ISI
SICI code
0040-4039(19991001)40:40<7275:ADATCA>2.0.ZU;2-4
Abstract
A seven-step synthesis of the 1-methyl-3-(o-azidophenyl)quinolin-2-one, a c ommon intermediate for the synthesis of the cryptotackieine and cryptosangu inolentine alkaloids, is described. This intermediate is directly converted into cryptotackieine 1 by an intramolecular aza-Wittig reaction with trime thylphosphine; alternatively heating followed by reduction of the resulting indoloquinoline derivative provided cryptosanguinolentine 2. (C) 1999 Else vier Science Ltd. All rights reserved.