Chiral azole derivatives, 3. Synthesis of the enantiomers of the potent aromatase inhibitor 1-[2-benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole

Authors
Messina, F Botta, M Corelli, F Mugnaini, C
Citation
F. Messina et al., Chiral azole derivatives, 3. Synthesis of the enantiomers of the potent aromatase inhibitor 1-[2-benzofuranyl(4-chlorophenyl)methyl]-1H-imidazole, TETRAHEDR L, 40(40), 1999, pp. 7289-7292
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
40
Year of publication
1999
Pages
7289 - 7292
Database
ISI
SICI code
0040-4039(19991001)40:40<7289:CAD3SO>2.0.ZU;2-L
Abstract
Starting from (+)- and (-)-1-(4-chlorophenyl)-2-propynylamine, in turn obta ined by CAL-mediated kinetic resolution of the corresponding racemate, a st ereoselective synthesis of both enantiomers of the title compound has been achieved. (C) 1999 Published by Elsevier Science Ltd, All rights reserved.