Antimicrobial activity studies of the binuclear metal complexes derived from tridentate Schiff base ligands

Three novel tridentate Schiff base ligands derived from the 3-hydroxysalicy laldehyde (H2L1), 4-hydroxysalicylaldehyde (H2L2) and 5-bromosalicylaldehyd e (H2L3) with a new amine N-(pyridyl)-2-hydroxy-3-methoxy-5-aminobenzylamin e (2) have been prepared. The ligands and their metal complexes have been c haracterized by elemental analyses, conductivity and magnetic susceptibilit y measurements, i.r., electronic absorption and H-1 and C-13 n.m.r. spectro scopy. All complexes are binuclear and, in some, the H2O molecules are coor dinated to the metal ion. Antimicrobial activities of the ligands and their complexes have been tested against to the Bacillus subtilis IMG 22 (bacter ia), Micrococcus luteus LA 2971 (bacteria) Saccharamyces cerevisiae WET 136 (yeast), and Candida albicans CCM 314 (yeast). Thermal properties of all c omplexes have been studied by t.g. and d.t.a techniques.