Mitochondrial genomes are being used to study increasingly ancient divergen
ces among animal groups. Recent studies of complete mitochondrial DNA seque
nces have arrived at somewhat heretical conclusions, raising questions abou
t the use of mitochondrial gene sequences for studying the relationships am
ong highly divergent lineages. Other studies have documented convergent evo
lution of mitochondrial gene order, casting doubt on the use of these chara
cters for phylogenetic analysis. The use of mitochondrial genomes for study
ing such deep divergences is coming under increased scrutiny, and these nov
el results need to be confirmed with data from nuclear genes.