Evidence for immunosuppression associated with Jembrana disease virus infection of cattle

Authors
Wareing, S Hartaningsih, N Wilcox, GE Penhale, WJ
Citation
S. Wareing et al., Evidence for immunosuppression associated with Jembrana disease virus infection of cattle, VET MICROB, 68(1-2), 1999, pp. 179-185
Citations number
12
Categorie Soggetti
Veterinary Medicine/Animal Health",Microbiology
Journal title
VETERINARY MICROBIOLOGY
ISSN journal
03781135 → ACNP
Volume
68
Issue
1-2
Year of publication
1999
Pages
179 - 185
Database
ISI
SICI code
0378-1135(19990816)68:1-2<179:EFIAWJ>2.0.ZU;2-H
Abstract
Jembrana disease virus (JDV) is a newly recognised bovine lentivirus causin g an acute disease syndrome in Ball cattle (Bos javanicus) in Indonesia. We evaluated the effect of JDV infection on the antibody response to chicken ovalbumin (cOVA) and Brucella abortus Strain 19 in Ball cattle. In infected cattle the IgG and IgM response to cOVA was suppressed and delayed and the IgG response to B. abortus Strain 19 was delayed. The results indicate tha t the humoral immune response is suppressed and delayed in JDV infected cat tle. (C) 1999 Elsevier Science B.V. All rights reserved.