Objectives. This study examined injection drug use among homeless men
and women with severe mental illness in two sites. Methods. The data w
ere drawn from related clinical trials conducted in Baltimore (101 men
. 49 women) and Boston (85 men, 33 women). Results. The percentages of
homeless men with a history of injection drug use were 26% in Baltimo
re and 16% in Boston. the corresponding rates among homeless women wer
e 8% and 6%. Conclusions. Taken together, these and previous results s
uggest high lifetime prevalences of injection drug use-and associated
risks of HIV transmission-in this elusive population.