The aim of this study was to evaluate the treatment and outcome of patients
with local recurrence (LR) of differentiated thyroid carcinoma. This retro
spective study concerned patients treated between 1974 and 1990 for papilla
ry or follicular thyroid cancer. Our patients had at least one LR. LR diagn
osed within 6 months after thyroidectomy and patients with increased serum
thyroglobulin levels were excluded. Thirty one patients (80 % female) aged
15 to 84 years had at least one LR. LR was diagnosed 7 to 200 months after
thyroidectomy (mean 63.7). There were 25 papillary and 6 follicular cancers
. There were 1.5 LR per patient (range 1-6). LR were treated by radioiodine
in 21 cases and by surgery in 22 cases. Among the 22 surgically treated pa
tients, 7 had nodal recurrences, 7 had nodes and tumor, 3 had only tumor, 1
had recurrence in the remnant thyroid. After a mean follow-up of 75.8 mont
hs, II patients had distant metastases, 11 had died from their thyroid carc
inoma (7 after metastases). Three of the 7 patients with nodal recurrence d
ied. In one third of cases, LR announced distant metastases. Node recurrenc
e had a poor prognosis.