Determination of arsenic speciation by capillary electrophoresis and ICP-MS using a movable reduction bed hydride generation system

The movable reduction bed hydride generation (MRBHG) system, a new hydride generation technique developed for coupling of CE with ICP for the determin ation of some hydride-forming elements, has been modified to realize the su ccessful coupling of CE with ICP-MS. The modifications focused on decreasin g the RSD and improving the detection Limits. The parameters not studied in our previous work, such as transport tubing length, moving rate of movable bed and carrier gas, were investigated to obtain a deeper understanding of the system. The modified system has been successfully used as an interface for CE and ICP-MS, and the hyphenated technique has also been applied to t he determination of four arsenic species in a Chinese medicine using standa rd addition. The recoveries of As(III), DMA, MMA, and As(V) were 105.4% (+/ -0.5%), 85.0% (+/-0.4%), 108.0%(+/-0.5%), and 88.3%(+/-0.4%), respectively.