ANTIBIOTIC-SENSITIVITY PATTERNS OF ACTINOMYCETES ISOLATED FROM PATIENTS OF ACTINOMYCETOMA

The effectiveness of eight antibiotics against 30 human isolates of ac tinomycetoma agents belonging to 7 different species were tested by ag ar dilution and disc diffusion methods to evaluate the susceptibility patterns and to study drug resistance among the organisms. It was foun d that many of the isolates had developed partial or complete resistan ce to conventionally used antibiotics like cotrimoxazole, streptomycin and ampicillin, but almost all were sensitive to amikacin and ciprofl oxacin. The two methods were equally effective for detecting sensitivi ty patterns of the Nocardia isolates.