M. Botta et al., Synthesis and biological evaluation of 2-methoxy- and 2-methylthio-6-[(2 '-alkylamino)ethyl]-4(3H)-pyrimidinones with anti-rubella virus activity, BIO MED CH, 7(9), 1999, pp. 1925-1931
The synthesis of a new family of antiviral compounds, 2-methoxy-, and 2-met
hylthio-6-[(2'-alkylamino)ethyl]-4(3H)-pyrimidinones, has been accomplished
. The activity of these agents against positive strand (rubella virus and s
indbis virus) and negative strand (vesicular stomatitis virus) RNA viruses
is reported. Some of these compounds are efficient and selective inhibitors
of rubella virus. (C) 1999 Elsevier Science Ltd. All rights reserved.