New therapeutic alternatives to portal vein thrombosis (PVT) include the pe
rcutaneous, transhepatic infusion of fibrinolytic agents, balloon dilatatio
n, and stenting. These maneuvers have proven to be effective in some cases
with acute, recent PVT. We have treated two patients with acute PVT via tra
nshepatic or transjugular approaches and by using pharmacologic and mechani
cal thrombolysis and thrombectomy. Although both patients clinically improv
ed, morphologic results were only fair and partial rethrombosis was observe
d. The limitations of percutaneous procedures in the recanalization of acut
e PVT in noncirrhotic patients are discussed.