I. Calis et al., Phenylethanoid glycosides from Digitalis ferruginea subsp ferruginea (=D-aurea LINDLEY) (Scrophulariaceae), CHEM PHARM, 47(9), 1999, pp. 1305-1307
Two new phenylethanoid glycosides, ferruginoside A (3,4-dihydroxy-beta-phen
ylethoxy-O-beta-D-glucopyranosyl- (1-->6)-2-O-caffeoyl-beta-D-glucopyranosi
de) and ferruginoside B (3,4-dihydroxy-beta-phenylethoxy-O-beta-D-glucopyra
nosyl (1-->6)-beta-D-glucopyranoside) were isolated, along with the known c
ompounds lugrandoside and transferulic acid, from the aerial parts of D. fe
rruginea subsp. ferruginea. For structural elucidation of the isolates, che
mical transformation (acetylation, methylation, alkaline hydrolysis), one a
nd two dimensional (COSY, HMQC, HMBC, ROESY) NMR techniques and FAB-MS were
used.