There is increasing interest in evaluating the methods used to implement th
e findings from medical research. This paper describes the Evidence-based O
utReach (EBOR) trial, which is the first large randomized study in the Unit
ed Kingdom that will evaluate the effectiveness and efficiency of education
al outreach visits by trained pharmacists who are delivering messages deriv
ed from four evidence-based clinical practice guidelines. General practices
form the unit of allocation and analysis. The study design addresses impor
tant factors that may influence the effectiveness of the intervention, such
as the pharmacist who delivers the messages, the health authority in which
practices are located, and the size of a practice. (C) Elsevier Science In
c. 1999.