Few studies have focused on the impact of gastroesophageal reflux disease o
n general health and on work absenteeism. Our aim was to evaluate the preva
lence and severity of symptoms suggestive of gastroesophageal reflux diseas
e in two samples of Italian employees, We interviewed 424 subjects of S, Ma
tteo Hospital staff and 344 subjects of the Military Factory of Pavia regar
ding the frequency and severity of heartburn and acid regurgitation during
the last 12 months. Subjects were specifically asked whether symptoms inter
fered with the quality of work activities or determined work absenteeism. I
n all, 91% of eligible subjects responded. The prevalence rate per 100 of a
ny heartburn or regurgitation experienced at least monthly was 21, This val
ue increased to 45% taking into consideration symptoms experienced occasion
ally. Mild or moderate symptoms were more frequent than severe symptoms (P
< 0.001). Only 2.6% of subjects answered that symptoms have a negative infl
uence on the quality of their work. No work absenteeism was recorded. The s
tudy confirms that typical gastroesophageal reflux symptoms are common cond
itions, but mainly of mild or moderate degree.