Unstructured kinetic model for sophorolipid production by Candida bombicola

Citation
F. Garcia-ochoa et Ja. Casas, Unstructured kinetic model for sophorolipid production by Candida bombicola, ENZYME MICR, 25(7), 1999, pp. 613-621
Citations number
18
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
ENZYME AND MICROBIAL TECHNOLOGY
ISSN journal
01410229 → ACNP
Volume
25
Issue
7
Year of publication
1999
Pages
613 - 621
Database
ISI
SICI code
0141-0229(199910)25:7<613:UKMFSP>2.0.ZU;2-G
Abstract
A kinetic model for sophorolipid production by Candida bombicola is propose d. The unstructured nonsegregated kinetic model takes into account three re sponses: biomass, sugar, and sophorolipid. In the kinetic model, the nitrog en-from yeast extract-is assumed to be the limiting nutrient of the yeast g rowth, the sugar-glucose-is assumed to be used in both growth and sophoroli pid production, and oil is supposed to be spent in product formation and ma intenance of biomass is attributed to glycerol eased by the catabolism of t he oil. The parameters of the kinetic model are calculated by fitting model to experimental data. These data have been obtained in experiments in whic h a batch stirred and an aerated tank bioreactor have been used. Fitting ha s been carried out according to a nonlinear regression algorithm, coupled w ith a Runge-Kutta method for the interpretation of integral data (evolution of system composition with time). The proposed kinetic model is able to ex plain both our experimental data and data given by other authors in previou s works in literature in which nutrient and product concentrations evolutio n are given. (C) 1999 Elsevier Science Inc. All rights reserved.