SEER data, corpus uteri cancer: Treatment trends versus survival for FIGO stage 11, 1988-1994

Objective. 1998 Surveillance, Epidemiology, and End Results (SEER) data est imate an 83.1% 5-year survival rate for corpus uteri adenocarcinoma FIGO st age II. The SEER data were evaluated to determine whether primary treatment differences using simple hysterectomy or radical hysterectomy, with or wit hout radiation, altered disease survival. Materials and Methods. SEER incidence data for FIGO II uterine corpus cance r of adenocarcinoma histology from 1988 to 1994 were stratified by hysterec tomy type (simple versus radical) and whether radiation was given. Survival rates were calculated using a relative survival method and are expressed a s percentages. Statistical analysis was done using a Z test. Results. The 5-year cumulative survival rate for patients with stage II ute rine corpus adenocarcinoma who received surgery alone as primary therapy wa s 84.36% with simple hysterectomy and 92.96% with radical hysterectomy (P < 0.05). Survival for patients who received combination radiation and surger y as primary therapy was 82.77% with simple hysterectomy and 88.02% with ra dical hysterectomy (P < 0.05). Pelvic and para-aortic nodes were negative. There was no significant survival difference for radiation versus no radiat ion in either surgical group. Conclusion. Radical hysterectomy is associated with better survival when co mpared to simple hysterectomy for FIGO LI corpus uteri adenocarcinoma.