PEROXIDATION POTENTIAL OF RAT THYMUS DURING DEVELOPMENT AND INVOLUTION

Authors
GALLI MC CABRINI L CABONI F CIPOLLONE M LANDI L
Citation
Mc. Galli et al., PEROXIDATION POTENTIAL OF RAT THYMUS DURING DEVELOPMENT AND INVOLUTION, Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology, 107(3), 1994, pp. 435-440
Citations number
25
Categorie Soggetti
Biology,"Pharmacology & Pharmacy",Toxicology
Journal title
Comparative biochemistry and physiology. Part C, Pharmacology toxicology & endocrinology → ACNP
ISSN journal
13678280
Volume
107
Issue
3
Year of publication
1994
Pages
435 - 440
Database
ISI
SICI code
1367-8280(1994)107:3<435:PPORTD>2.0.ZU;2-4
Abstract
The thymus of rats of ages between 1 and 7 months was homogenised and subjected to oxidative stress induced by iron salts. Lipid peroxidatio n, protein thiols and glutathione status were evaluated. The thymus of rats of 1 month of age exhibited lower susceptibility to the radical attack with respect to the thymus of rats between 3 and 7 months of ag e. This susceptibility was correlated with the content of polyunsatura ted fatty acids and of lipophylic chain-breaking antioxidants.