Hg-coordination studies of oligopeptides containing cysteine, histidine and tyrosine by Hg-199m-TDPAC

Citation
B. Ctortecka et al., Hg-coordination studies of oligopeptides containing cysteine, histidine and tyrosine by Hg-199m-TDPAC, HYPER INTER, 121(1-8), 1999, pp. 737-743
Citations number
12
Categorie Soggetti
Physics
Journal title
HYPERFINE INTERACTIONS
ISSN journal
03043843 → ACNP
Volume
121
Issue
1-8
Year of publication
1999
Pages
737 - 743
Database
ISI
SICI code
0304-3843(1999)121:1-8<737:HSOOCC>2.0.ZU;2-N
Abstract
In order to study the interaction of histidine- and tyrosine-containing pep tide chains with Hg(II), the nuclear quadrupole interaction (NQI) of Hg-199 m in the Hg complexes of the oligopeptides Alanyl-Alanyl-Histidyl-Alanyl-Al anine-amid (AAHAA-NH2) and Alanyl-Alanyl-Tyrosyl-Alanyl-Alanine-amid (AAYAA -NH2) was determined by time differential perturbed angular correlation and is compared with previous data on Alanyl-Alanyl-Cysteyl-Alanyl-Alanyl (AAC AA-OH). The Hg-199m-NQIs depend on the oligopeptide to Hg(II) stoichiometry and indicate that two-fold and four-fold coordinations occur for the bound Hg(II).