The absence of ejaculation in two patients treated with risperidone is desc
ribed. This side-effect has rarely been reported. The mechanism responsible
for ejaculation dysfunction in risperidone treated patients is unclear, bu
t might be due to the alpha(1)-adrenergic antagonist action of the drug. In
t Clin Psychopharmacol 14:317-319 (C) 1999 Lippincott Williams & Wilkins.