We built a modified version of voltage gradient gel electrophoresis system
to correct distortions in nucleic acids electrophoretic migration patterns
occurring at the edges of the gel when the original voltage gradient appara
tus is used. The new device allows correct fractionation of nucleic acids a
lso when electrophoresis is performed at high voltages. (C) 1999 Elsevier S
cience BN. All rights reserved.